Anti-inflammatory and Analgesic Activity of Methanolic Extract of Medicinal Plant Rhodiola rosea
Rhodiola rosea L. (Crassulaceae) have been used as traditional medicines that can increase someone’s physical strength, work productivity, longevity and resistance to high altitude sickness, fatigue, depression, anaemia, gastrointestinal ailments, infections, and nervous system disorders.
INTRODUCTION Rhodiola rosea, also known as “golden root” or “roseroot” belongs to the plant family Crassulaceae. For past few centuries, rhizomes of this plant has been used in the traditional medicine of Russia, Scandinavia, and other countries. In the rhizome it stores the secondary metabolites that have been shown to possess different medical activities and valuable adaptogenic effects. Traditional folk medicinal system used R. rosea to increase physical endurance, work productivity, longevity, and resistance to high altitude sickness, fatigue, depression, anaemia, impotence, gastrointestinal ailments, infections, and nervous system disorders
Inflammation was described two thousand years ago by Celsus by the four Latin words: Rubor, calor, tumor and dolor. Inflammation has different phases. The first phase iscaused by an increase of vascular permeability resulting in exudation of fluid from the blood into the interstitial space, the second one by infiltration of leukocytes from the blood into the tissues and the third one by granuloma formation